The NIH Guidelines for Research Involving Recombinant DNA Molecules addresses which of the following?

The NIH Guidelines for Research Involving Recombinant DNA Molecules addresses which of the following?

• A. Handling of recombinant-DNA-containing microorganisms
• B. Transportation of animals infected with recombinant-DNA-containing microorganisms
• C. Welfare of animals infected with recombinant-DNA-containing microorganisms
• D. All of the above

Answer: (A)

Regulatory focus: the NIH Guidelines set out how to safely conduct research involving recombinant DNA, emphasizing containment and handling of recombinant-DNA-containing microorganisms. They specify practices, facilities, equipment, training, and oversight to prevent exposure or release, with responsibilities met through institutionally based biosafety programs and Institutional Biosafety Committees. This guidance is about performing the work safely and responsibly, not about transporting animals or addressing animal welfare in a broader regulatory sense. Transportation of animals and welfare concerns are governed by other regulations—such as those under the Animal Welfare Act and IACUC oversight—so they fall outside the NIH Guidelines. Therefore, the provision that matches the question is the handling of recombinant-DNA-containing microorganisms.

Regulatory focus: the NIH Guidelines set out how to safely conduct research involving recombinant DNA, emphasizing containment and handling of recombinant-DNA-containing microorganisms. They specify practices, facilities, equipment, training, and oversight to prevent exposure or release, with responsibilities met through institutionally based biosafety programs and Institutional Biosafety Committees. This guidance is about performing the work safely and responsibly, not about transporting animals or addressing animal welfare in a broader regulatory sense. Transportation of animals and welfare concerns are governed by other regulations—such as those under the Animal Welfare Act and IACUC oversight—so they fall outside the NIH Guidelines. Therefore, the provision that matches the question is the handling of recombinant-DNA-containing microorganisms.