AALAS Laboratory Animal Technologist (LATG) Practice Test

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Which statement describes the sugar in DNA?
Which ABSL level relates to infectious agents that cause serious or potentially lethal diseases when inhaled?
Which of the following routes is considered parenteral?
Which type of culture system is used to grow viruses?
When DNA fragments are produced by an investigator, which test is used to determine if the desired fragment is present?
Which organization or document is primarily associated with establishing biosafety levels for work with infectious agents?
Planning your work by prioritizing activities into high, medium, and low levels is a function of which management tool?
What color do Gram-negative organisms retain when exposed to Gram stain?
Which sugar is found in the DNA backbone?
The term for drugs like atropine and glycopyrrolate is best described as:
Which statement describes an exception to the euthanasia requirement for sick or stressed animals under the Animal Welfare Act?
Which of the following is a sign that indicates good maternal care and good pup health?
What is the method generally used to decontaminate large volumes of contaminated bedding?
What is a main factor for determining the number animals used as sentinels?
What laboratory animal species is especially prone to scurvy caused by a vitamin C deficiency?
Acariasis is the medical term for infestation by which group of organisms?
Which of the following actions is a core management function?
Xylazine provides analgesia in addition to sedation. Which statement best describes this property?
A nonrebreathing system is used for animals of what body weight range?
Suspensions are liquids in which the drug is dissolved.
An abnormal urinalysis may indicate disease of which organ of the body?
Which leadership style aligns with empowering staff by giving them ownership of tasks?
Which graft type involves transplantation within the same individual, such as moving tissue from one site to another?
Which condition may cause enterotoxemia in guinea pigs?
A serious complication associated with tribromoethanol is which?
In AIDS, the HIV virus destroys which of the cells involved in the immune response?
What is a typical rationale for moving sentinel cages around the room in a microbiology facility?
Which of the animals described below would be best to use as a sentinel in a room housing a mouse colony?
The presence of most bacteria in a sample can be confirmed by culture on artificial media.
What is the best method of stopping the function of a specific gene?
What is the main purpose of organizing in facility management?
Which method is used to identify Salmonella, Shigella, and Streptococcus by detecting surface antigens?
What is another name for an axenic animal?
Why are inbred strains preferred when creating transgenic mice?
Ibuprofen is the trade name of a pain reliever.
Which activity is not required to have a standard operating procedure per the FDA Good Laboratory Practice regulations?
Flukes are a common parasite of laboratory animals.
Heartworm infection in dogs may be diagnosed using an ELISA test.
If two hemizygous transgenic mice are crossed, what fraction of offspring carry the transgene?
Which statement best describes the final step in the recommended hiring sequence?
The basic resistance you are born with is called _________.
Xylazine is a sedative that has an analgesic effect.
Which document provides guidelines for the care and use of laboratory animals?
Which term describes bacteria that thrive in environments with reduced oxygen levels?
Which statement applies to propofol?
Canine parvovirus is found only in very young animals. True or False?
In what pain category would you place animals which were subjected to pain but did not receive anesthetics or analgesics to relieve their pain because it would have adversely affected the procedure or the result?
Ketamine is classified as which type of drug?
In which of the following routes of administration, would a drug have the slowest rate of absorption into the bloodstream?
Miconazole is effective against which type of pathogens?
Antibiotic treatment in guinea pigs can predispose to which condition?
Serum is the liquid portion of clotted blood.
Which signaling approach is suggested as an alternative to traditional fire alarms to reduce noise?
Which approach is most efficient when you have limited time and multiple urgent items?
What is the term for a drug that can reverse the effect of another drug?
An inadequate quality assurance program can compromise the _________ and _______________ of the experimental results.
Pink mucous membranes indicate what about oxygenation?
There are ___ micrometers in one millimeter.
If you need serum for a test, you should use a syringe without an anticoagulant.
All diseases that affect the immune system cause a decreased immune response.
What is the recommended first step for efficiently planning your work each day?
Ivermectin, fenbendazole, and pyrantel pamoate are all used to treat animals for:
Hydatid cysts are associated with which parasite type?
Which phrase best describes "immune response"?
What is one of the indexes used to measure the breeding performance in genetic monitoring?
Which of the following statements is true for buprenorphine?
What are the units for specific gravity?
Which reason would be sufficient to terminate an employee?
Yeasts are unicellular fungi.
Which immunoglobulin is associated with hypersensitivity reactions such as asthma?
The animal care and veterinary technicians are the first responders when a security breach occurs in a facility.
To test nonhuman primates for tuberculosis, tuberculin is injected intradermally in which part of the body?
A polyvalent vaccine is sometimes called a multivalent vaccine; which statement is true?
Which of the following elements describes a good performance standard?
What is the first antibody which is detected in response to an initial exposure to an antigen?
Medical waste as defined by the Medical Waste Tracking Act of 1988 does NOT include which of the items listed below?
Which condition in newly set up fish tanks is most likely associated with lethal toxic buildup?
Once a goal has been established for the unit, which of the following issues should the manager first consider?
An MSDS provides _____________ data and ___________ information.
HEPA filters remove waste gases from the air.
How is a mycelium formed?
Transfer of soiled bedding to sentinel cages is generally an effective way to detect the presence of mouse hepatitis virus in a colony.
Which statistic describes how measurements deviate from the mean?
The choice of the statistical tests that will be used in a study is made:
Which statement correctly describes vitamin C deficiency in relation to scurvy?
Which statement best describes the purpose of randomization?
Where are ectoparasites normally found on a rabbit?
In a study on whether a food treat helps rats to learn a specific behavior more quickly, what would be the minimum number of groups that you would need?
Which of the following drugs can reverse the effect of opioids?
Which leukocyte is most commonly associated with allergic reactions and parasitic infections?
Which statement best describes the purpose of hybridoma technology?
LATGs can contribute to unit goals because of their knowledge of which areas?
What does the W symbol on the NFPA hazard diamond indicate?
In nonhuman primates, tuberculin testing involves intradermal injection in which location?
What are hydatid cysts?
Which groups are typically involved in conducting an occupational health and safety risk assessment?
Which statement best describes how to prevent injuries inflicted by animals in the facility?
Diploid cells have chromosomes that exist in pairs, indicating they contain how many chromosome sets?
What is another term for macrophages?
What technique allows a mouse strain to be taken 'off the shelf' but still be available for use when needed?
The intermediate hosts for the tapeworm Dipylidium caninum are fleas or lice.
In DNA, which base pairs with adenine?
Which type of training is NOT required by the Animal Welfare Act?
The term "slow viruses" is often used to describe which group?
Which of the following is not a good security measure?
If two homozygous transgenic animals are mated, what percentage of offspring will be homozygous for the transgene?
Which best describes progressive discipline?
What is an appropriate approach when you observe unsatisfactory behavior?
Are all animals produced by pronuclear injections of the same transgene guaranteed to have the same phenotype and genotype?
Which of the following rodent diseases might show signs that could be misidentified as having been caused by biting or fighting?
Which statement is true of mouse hepatitis virus?
Which of the following can help the technologist observe the pups without disturbing the mother?
Canine heartworm disease can be detected by fecal examination.
GLP regulations apply to safety assessment for which groups?
Genetic drift describes which phenomenon?
Why is neomycin NOT given by the parenteral route?
Bacillus stearothermophilus is best described as which type of organism?
What document states that an animal facility must develop a disaster plan?
If a gaseous anesthetic has a higher vapor pressure, what does this indicate about its volatility?
Which law/regulation has an impact on employment practices?
Which term describes animals that were germ-free at origin and later inoculated with a defined microbial group?
Pentobarbital and propofol are examples of what type of drug?
The numbers of animals purchased by a researcher are usually tracked against which of these numbers?
Enteral administration of a drug refers to which of the following?
Which of these agencies have regulations or guidelines that regulate the transportation of animals?
The statement 'Animals must always be administered the drug dosage recommended by the manufacturer for the animal species to be treated' is true.
What is the key to providing job variety in a facility?
Genotype testing is generally performed using which of the following methods?
Which statement best describes alpha particles?
Who should approve the number of animals to be purchased for a study according to the protocol?
Which individuals or groups have a responsibility in developing and implementing the components of the institution's occupational health and safety program?
The buffy coat in the hematocrit tube can be collected and used to:
What ABSL level is used for working an infectious agent that is well characterized and known to not cause disease in humans?
What is the best age to genotype a mouse in order not to disturb the litter?
Who regulates the importation of animals such as dogs, cats, and turtles?
Cyanosis relates to which condition?
According to the Guide for the Care and Use of Laboratory Animals, who should represent the animal facility on the institution's safety committee?
Which statement about the phosphate group in DNA is true?
Coxiella burnetii is the causative agent for which disease?
Antibodies are produced by which type of cells?
Which of the following can be a consequence of the introduction of vermin into the facility?
What role do enzymes play in the body?
Which device is used to monitor pulse rate and oxygenation during anesthesia?
Which statement best describes the relationship between decentralized facilities and researchers?
The more volatile the anesthetic gas is, the higher its vapor pressure is.
Which of the following provides a measure of an animal's pulse rate?
Which approach helps maintain productivity when workloads fluctuate?
What disease can cause fatal respiratory disease in newborn and weanling mice?
Which of the following routes of administration requires that the animal be sedated or anesthetized?
Which of the following is the mathematical average of all measurements in a data set?
What term describes disruption of endogenous genes caused by the integration of a transgene into the genome?
What is another name for white blood cells?
Rabbits rid themselves of gastric trichobezoars by vomiting.
The pinworm Aspiculuris tetraptera can be detected in mice by the anal tape test.
Which of the following is an example of 'job variety'?
What pathogen is often prevalent in conventional rodent colonies?
What is cross-fostering?
Dipylidium caninum uses which type of host during its lifecycle?
Using isolator caging to prevent microorganisms from reaching the animals housed inside is best described as which term?
In rabbits, genital infections with mucopurulent nasal and ocular discharge are most commonly associated with which disease?
Which statement best reflects the role of staff in improving security SOPs?
Before changing workloads, what is a recommended first step?
Which of the following are NOT used in the production of chimeras?
What is the role of the pop-off valve in a rebreathing system?
Lice share which of the following characteristics?
An animal supplier's health status report is an assurance that the animals arriving in the facility are healthy and free of pathogens.
What is the non-vertebrate vector for the malarial parasite Plasmodium?
Gram staining differentiates bacteria; Gram-negative appear red or pink.
Which statement is true regarding non-human primates under the 1989 amendments?
New tank systems can cause high levels of __________ in the water that may kill fish.
The term 'nits' refers to what in lice biology?
How often should vital parameters be recorded in the anesthetic log for each animal?
Gastric trichobezoars in rabbits are best described as which presentation?
What is the confidence level?
A case history consists of the complete list of the findings obtained during necropsy.
What is the term for an area on an antigen that is recognized by the immune system as nonself?
In hysterectomy derivation, the fetuses are typically obtained at which developmental stage?
Who is typically responsible for space management in a facility?
Only a segment of DNA which originated in a living organism can be used as a transgene.
Installing smoke detectors would be considered what type of disaster-related activity?
Which of the following measures would not be practical in instituting an effective facility security plan?
What is the most widely used parasiticide in laboratory animal medicine?
Which statement describes gamma radiation?
Sharps can be disposed of in regular trash cans as long as there is a biohazard sign on the trash can.
Some fungi produce spores as a means of reproduction.
Which is NOT a common gastrointestinal condition observed in laboratory rabbits?
What is the correct genetic designation for the initial founder of a line of transgenic mice?
A bolus is which of the following items?
What definition best describes the term maintenance dose?
Which pathogen would you suspect if a rabbit sneezes and has a nasal discharge and a head tilt?
Using the pronuclear injection technique, what is the average percentage of offspring carrying the transgene?
What carries the cell's genetic information across the nuclear membrane?
In a laminar flow cabinet, the air flow is designed to be what?
For which of the following conditions are cephalosporins often used?
Which of the following is an example of a direct cost center?
If an animal tests negative for a pathogen 3 weeks after arrival at the facility, which conclusion is appropriate?
Nitrous oxide: which statement is true?
Which of the following steps is recommended in managing inspections?
Which process best describes histopathology?
Which setting increases the speed of electrons in X-ray production?
The term parenteral means "via the alimentary canal".
A biomolecule consisting of a chain of hydrocarbons is what type of compound?
Which of the following best describes the bonding capacity of an atom?
What is the first step in determining total cost accumulation?
What statement best describes the main characteristic of autoimmune disease?
Serum collected for testing should be drawn using a syringe without anticoagulant, because serum is the liquid that remains after blood has clot.
Which of the following characteristics applies to alpha particles?
ABSL-1 level work can be conducted on the open bench as long as good microbiological techniques are used.
Evaluating the unit's progress towards its goals and evaluating the individuals within the unit is called:
The AWA amendments of 1985 require enrichment for which species?
Where does transcription take place?
SOP is the acronym for which of the following?
In generation nomenclature for transgenic lines, what does F1 denote?
What term describes the complete killing of all living organisms?
Which of the following groups of viruses contain DNA?
In vaccine science, what is the main purpose of including adjuvants?
What does it mean when experimental results show a significant difference at a p-value of 0.05?
A micrometer is equivalent to __ of a meter.
Morphine is used for analgesia.
Establishing good containment safeguards for general waste helps prevent which of the following?
Enzymes are made up of what type of organic compound?
What is a common rationale for selecting donor females and foster mothers with different coat colors in axenic pup production?
A respirator must meet the standards of and be maintained in accordance with ______ specifications.
Chronic immune complex diseases involve which phenomenon?
In bacteria, the flagellum is primarily associated with which function?
How many days does it generally take for an animal to develop an immune response to an agent?
Which graft type involves transplantation between genetically different individuals of the same species?
Which of the following is the best way to manage first-aid kits for staff emergencies?
Which statement best describes plasma?
Which stage of anesthesia is typically associated with the loss of reflexes and readiness for surgery?
Why are space surveys performed during the cost analysis process?
In hazardous waste disposal practices in an animal facility, who bears the primary responsibility?
What best defines 'variable' as used in the biomedical research field?
In selecting a respirator, the most critical determinant is the nature and degree of possible hazard.
The facility security plan should clearly define the lines of authority in the event of a breach of security.
What causes female mice to become pseudopregnant?
Where on the body are enteric endoparasites most commonly found in laboratory animals?
Which of the following best describes the origin of flexible-film isolators?
Which of the following is a requirement for endotracheal intubation of any species?
What is the common term for infectious tracheobronchitis in dogs?
What is the purpose of adding an antibiotic resistance gene into a DNA fragment before inserting it in a cell?
What is identified as the greatest problem related to purchasing excessive supplies?
Electrophoresis is a technique used to___________ the DNA fragments.
Which part of the antibody primarily determines its unique specificity?
Pinworms belong to which group of helminths?
The fecal flotation test requires a larger sample than the one needed for the direct smear.
Which agency's inspection reports are publicly accessible via FOIA?
Which term represents the hereditary information present in an animal?
What is a reliable method to ensure an employee understands how to complete a task after instruction?
When treated for a bacterial infection, why may a hamster die following one or more injections of penicillin?
Which statement is true about bacteria's mitochondria?
Which group should collaborate on space management decisions?
Which animals are more susceptible to hypothermia while under anesthesia?
Which type of respiration is seen in normal, awake animals?
Which statement is a good example of appropriate feedback to give an employee about a job well done?
Bloat is another term for which condition?
What best defines a drug dose rate?
Which preservation method is commonly used to preserve tissues for histology?
What test refers to the percentage of blood occupied by cells?
Which statements apply to bacterial pneumonia in guinea pigs?
Which statement best describes the immune system of axenic animals relative to animals with normal microflora?
What disease or condition may be caused by stress due to shipment in frogs?
The NIH's publication Guidelines for Research involving Recombinant DNA Molecules contains guidelines for which of the following situations?
What statement best describes essential fatty acids?
Containment safeguards for general waste primarily address which issue?
What is the process of inhaling medications called?
Which cell lineage is affected in XID mice?
Which immune system cells secrete antibodies?
What best describes polyclonal antibodies?
Following the experimental design helps avoid introducing unwanted ___________ that could affect results.
In microisolation housing, sentinel bedding is sourced from which of the following relative to other cages in the room?
Knockout animals are useful to determine what kind of information?
Microbial pathogens are usually identified after being inoculated onto nutrient media and left to grow. True or false?
Which action is typically the first step in a progressive discipline process?
A hematocrit test determines which parameter?
In the recognition step of the acquired immune response, the antigen is called the __________ molecule.
Which term best describes embryonic stem cells?
What are the two kinds of acquired immune response?
Carbon-14, tritium, and Iodine-125 are all what type of element?
A low hematocrit may indicate which condition?
Which term describes animals whose microbial flora is completely known?
What type of drug is acetylpromazine?
The liquid portion of unclotted blood is called what?
What percentage of the genes in the genome of a mouse have a corresponding gene in the genome of humans?
Which of the following offices have some regulations which relate to medical waste?
Which comment is most appropriate when reviewing a completed task?
Which of the following is NOT a biological hazard?
An enteric coating prevents what from happening to the medication?
The ability to plan steps for achieving long-range goals is an example of what kind of managerial skills?
Which statement is a good example of separating the person from the behavior?
Under which of the following conditions will viruses grow?
Gnotobiotics refers to animals whose _____ is completely known.
Serological testing of animals at arrival is used to determine which of the following?
Which are the weakest bonds in DNA?
In a drug dosage form, the substance that contains the drug is called:
A finding of thrombocytopenia would most directly be associated with which condition?
In transgenic lineage nomenclature, which description corresponds to the first generation offspring of the founder?
Which term describes studies for safety assessment that are not clinical trials in humans?
The acquired immune system only develops an immune response after an antigen has entered the body.
What agency requires that every research facility must establish an Institutional Animal Care and Use Committee?
The term "slow viruses" is used to describe which of the following?
Increasing the ________________ increases the speed of the electrons in the X-ray machine.
Which management function involves creating and maintaining the structure for tasks and responsibilities?
Which observation frequency is specified for warm-blooded animals during inspections?
Which component is used to add or remove material from the isolator without breaking containment?
Which of the following can help prevent injuries inflicted by animals in the facility?
What is the function of a flagellum in a bacterium?
Which of the following is NOT a technique used in genetic monitoring?
Which of the following drugs is a dissociative agent?
Immune hypersensitivity is responsible for all of the following except:
What differentiates embryo transfer from hysterectomy derivation?
The buffy coat layer in a hematocrit tube represents the concentration of which cells?
Sulfonamides are best described as:
CFU is a unit used to quantify what kind of biological material?
Which sign is commonly observed with diarrhea in nonhuman primates?
Diabetes mellitus results from the abnormal secretion or action of what substance?
In pronuclear injection, why are some females mated to vasectomized males?
What are important precautions for personnel who handle hazardous waste?
Axenic animals generally have which of the following characteristics?
Platelets are a source of:
Establishing personal goals serves what primary purpose in a laboratory animal care setting?
How soon after exposure should a sentinel be tested for a specific pathogen?
Diazepam belongs to which drug class?
Heavy equipment, sharps, and animal bites are considered what type of occupational hazard?
Which of the following is not a function of management?
Which of the following viruses is an RNA virus that affects laboratory rodents?
Which resource provides guidance on radiograph settings for different animals in a radiology lab?
As a radioactive substance decays, the energy and particles emitted are referred to as:
In rebreathing anesthesia systems, what type of gas reaches the animal's lungs?
Which statement best reflects the nature of ongoing evaluations?
What is the best response when a nonhuman primate is found to have bloat?
Which characteristic is true of axenic animals as compared to animals with normal microflora?
In ongoing evaluations, what should be the primary focus?
Which of the following types of animals are considered gnotobiotes?
Exceeding the manufacturer's recommended dosage is never acceptable.
A bolus is best described as
What does the 'N' indicate in an N-95 type of respirator?
What is the product of translation?
Which statement about pinworm testing in rodents is correct?
Which factor influences success in producing axenic pups by hysterectomy derivation?
Which time frame of the animal's health status is revealed by serological tests on samples taken when animals arrive at the facility?
Which drug is commonly used to treat endoparasites?
During IACUC inspections, are breeding operations of vendors supplying animals for the research program required to be inspected?
Which vaccination is recommended for researchers who work with serum, blood, or tissues from humans or ape?
What is a balling gun used for?
The CDC is one of the agencies that regulates the care and welfare of research animals.
Which agencies share responsibilities relating to animal transportation?
Which immunoglobulin crosses the placenta and offers protection to the newborn during the first weeks of life?
The gauge at the top of the nitrous oxide tank is used to determine the amount left in the tank.
Which term describes the elimination of parasites by administering anthelmintic drugs to an animal?
Which virus in rats may increase anesthesia-related mortality but may be clinically silent?
In budgeting for an animal facility, a cost center is best described as:
Cestodes are categorized under which broad group of animals?
What does 'cloning DNA' mean?
Which definition best describes management?
Which statement best defines a genetic mutation?
What term describes animals that were originally germ-free but were given a known group of bacteria?
What term describes the time required for a radioactive substance to decay to half its activity?
Atropine and glycopyrrolate are which type of drug?
What is another term for the palpebral reflex?
Which publication provides clarifications and guidance in support of the Animal Welfare Act, as mentioned in the material?
The same vaporizer cannot be used for all anesthetic gases.
A secondary immune response to a given antigen is generally a weaker response than the primary response.
To properly prioritize tasks and assign work, which factors must be considered?
Which practice is emphasized to prevent contamination when handling donor females and foster mothers in axenic pup production?
Which statement correctly identifies Saprolegnia in aquatic settings?
A gavage needle is used for administering drugs to rodents using which route?
What is the term used for animals used in the health surveillance of rodent colonies?
The health surveillance program is a component of the quality assurance program.
The anal tape test is a valid method for detecting pinworms in mice.
An example of an in vitro experiment is one performed where?
Which statement is most consistent with an active viral infection based on neutrophil counts?
Imbalance in HDL and LDL is linked to which disease?
Passive immunity can be achieved by which method?
Which route of administration will produce the highest concentration in the bloodstream of a drug given at the same dose?
RBC values are usually given in what units?
What is a recommended action when preparing for an inspection?
Why is it recommended that sentinel cages be moved frequently around the room?
The US Drug Enforcement Administration has how many schedules of controlled substances?
A normal distribution is best described as which of the following?
An ELISA test used to diagnose heartworm infection in dogs detects which type of target?
Which hormone is used first in the superovulation protocol described for producing gene-targeted animals?
In which of the following scenarios could you be sure to obtain a mouse that is homozygous for the transgene?
TB testing is necessary for all personnel who work with nonhuman primates.
In rabbits, the disease presenting with genital infections and mucopurulent nasal/ocular discharge is called which?
What best describes a congenic strain?
Why are adjuvants used in vaccines?
When does replication occur in mammalian cells?
Which organism is most commonly associated with superficial fungal infections in animals?
Which of the following hematology test results is expressed as a percentage?
Which of the following is a characteristic of axenic animals?
What is the term for the natural mutations which cause animal strains to undergo change in genotype?
Which cell type is a component of the innate immune system?
Dipylidium caninum belongs to which group of parasites?
Which of the following is NOT a zoonotic disease?
An enteric-coated formulation is designed to dissolve in the intestines rather than the stomach.
What statement best describes the primary benefit of cryopreservation for mouse strains?
The secretion of antibodies occurs during which step of the acquired immune response?
Which of the following are potentially hazardous?
Which statement accurately characterizes ABSL-3 or higher levels?
Which statements apply to thiopental?
Which of the following best describes the term allele?
The goal of security-related SOPs is to make the facility staff 'rule enforcers'.
What must an investigator do to use an animal in more than one major operative experiment?
Which of these groups of compounds fall within the scope of the Good Laboratory Practices regulations?
The innate immune system provides the body with its first line of defense against foreign substances.
The thorny-headed worms are scientifically classified as which group?
What statement best describes a drug that is pyrogen-free?
Which statement about disaster planning best reflects its relationship to animal welfare and staff safety?
Which of the following signs might be an indication that the animal has ectoparasites?
Hematocrit is another term for packed cell volume.
Which description best defines bremsstrahlung?
Vapor pressure reflects what property of a gaseous anesthetic?
What percentage of the offspring of two homozygous parents will inherit the transgene?
Which committee is responsible for reviewing and approving animal care and use protocols in research laboratories?
A xenograft is a transplantation between which categories?
Which statement is true about antibody production in response to the same antigen?
In inventory documentation for controlled substances, which information is typically recorded?
What should be done in a biosafety cabinet prior to and upon completion of each work session involving a biohazard?
A HEPA filter removes particles that are _________ in diameter or larger.
To learn a new task, the supervisor should proceed by:
What term is commonly used to describe immunodeficient individuals?
Open bench work at ABSL-1 is permissible under which condition?
A generic antibody test is performed as an initial screen to identify which antibodies are present in the blood. Which of the following is true about this statement?
Which genetic modification method is most specific for inserting a transgene at a particular chromosomal location?
Which term represents an estimate of the reasonable level of a chemical to which a worker can be exposed without adverse effects?
In order to be used for inhalation administration, particles or droplets must be smaller than what size in diameter?
Which of the following best describes the detection of adventitious bacteria, viruses, or parasites at an early stage of infection in an animal facility?
Which of the following groups have regulatory authority to conduct unannounced inspections of the animal facility?
Sharps disposal policy: Is it acceptable to dispose of sharps in regular trash cans if there is a biohazard sign on the can?
Which statement best describes prostaglandin in the context of biomolecules?
What phrase best describes immunosuppression?
In applying the mirror principle, what should a supervisor do to influence employee behavior?
In a primate facility, which disease is viral in origin and can be transmitted from humans to nonhuman primates?
The best way to avoid high employee turnover is to:
In radiography, a structure described as radiolucent will appear darker on the image.
Establishing a structure would best describe which of the following?
Salmonella, Shigella, and Streptococcus are often identified using what method?
Which of the following characteristics does NOT apply to morphine?
In statistics, if you want to increase your confidence level, you should set your P value lower.
What must be done before terminating an employee?
The study of the fluid portion of blood with respect to the presence or absence of antibodies is called:
Which federal agency is typically associated with monitoring the use of radioactive materials in laboratories?
Penicillin is the best antibiotic to treat mice, rats, hamsters, and guinea pigs.
The organization's policies should be described in SOPs.
Depreciation of equipment is categorized as which type of cost in the budgeting framework?
Which two bacteria are commonly associated with pneumonia in guinea pigs?
What proportion of the offspring could you theoretically expect to be homozygous for the transgene if you mate two hemizygous parents?
The term 'anamnestic' is used to describe which type of immune response?
Drugs given enterally are absorbed more rapidly and completely than those given intravenously.
Which term describes a condition in which the immune system shows reduced responsiveness?
Gram-negative organisms are found in the intestinal flora of many species.
If there is a delay of 12 to 24 hours after death before necropsy, what is the best approach to preserve the carcass?
What does the term gnotobiotics mean?
The major histocompatibility complex proteins are found on the surface of what type of cells?
Which organism is not a fungus?
Which of the following order of steps should be followed to produce gene-targeted animals?
According to PHS, all animals should be housed in a manner that __________ and __________.
Which groups are typically involved in conducting an occupational health and safety risk assessment?
Dividing the workload is defined as which activity?
What is the most common route of infection for Mycobacterium tuberculosis and M. bovis?
B virus belongs to which group of viruses?
Which molecule carries genetic information across the nuclear membrane to direct protein assembly?
The insulin-secreting tumor in ferrets is located in which organ?
What is the role of MHC proteins?
Providing a retirement plan to staff fits in which level of Maslow's hierarchy?
Which laboratory rodent is particularly prone to suffer from epileptic seizures?
Which cabinet provides a cage environment with linear-flowing filtered sterile air?
When prioritizing workload, which factor is least relevant?
Which test gives information on blood cell morphology?
Where is low-level radioactive waste generally stored?
Which statement about fungi is true?
Which statement best describes endoparasite treatment in laboratory animals?
The volume of the rebreathing bag in an anesthesia system should be about ___ times the animal's tidal volume.
Which of the following is part of the IACUC inspection criteria?
Which of the following would help maintain genetic integrity when producing axenic pups by hysterectomy derivation?
Which tissue-to-fixative ratio is typical for preserving tissue for histology?
In gerbils, which stressor can trigger epileptic seizures?
In which area is the term LAA specifically used, as described in the material?
Which unit is used to describe light intensity in this context?
Giardia spp. are flagellates that inhabit which region of the host?
After exposure to an antigen, which period represents when no antibody can be detected yet?
The mice resulting from the mating of a wild type with a chimera having a transgene in its germ cells will be __ for this mutation.
How should a urine sample for microbiological analysis be obtained?
What is a potential hazard related to the use of lasers during surgery?
Which biosafety cabinet class is designed to protect the user against direct contact with the cabinet contents?
Which of the following is not a basic step in the cost analysis of an animal resource facility?
Kaopectate is the most widely used drug to treat which condition in laboratory animals?
What is the most common mode of transmission of Microsporidia?
Are genes many chromosomes joined together?
Which training item is explicitly not required under the Animal Welfare Act?
Where can you set the desired concentration of anesthetic gas in a rebreathing system?
Why are per diem rate increases problematic for researchers?
Levels of light intensity above what level can cause retinal damage in albino animals?
Which organism is identified by a cecal exam postmortem?
Which source of animals is most likely to have internal parasites?
During their inspection, how often will IACUC members want to see documentation showing warm-blooded animals are observed?
Which statement best explains why, in a gene-targeted mutation, the DNA fragment is inserted at a specific locus?
Which statements apply to ketamine?
Providing a palatable food mixed with a drug is the least stressful way to medicate an animal.
What factors should determine the selection of a respirator?
What is a good way to encourage two people to resolve an interpersonal conflict?
Which animal group does NOT need to be routinely fasted before anesthesia?
Buying insurance to defray the cost of repairing the facility following a disaster would be considered what type of disaster-related activity?
The NIH Guidelines for Research Involving Recombinant DNA Molecules addresses which of the following?
Which of the following best defines drug clearance?
What are pronuclei?
A hematocrit is used to determine the:
When deriving axenic animals, microbiological monitoring should verify that which organism has not passed transplacentally to the pups?
A ___________ is a flexible plastic tube used to add material to or remove material from the isolator.
What is needed to obtain controlled substances in an animal facility?
Which best defines the term "immunology"?
In microisolation cages, which factor affects the temperature and humidity level?
When receiving animals at an institution, which of following is not a matter needing attention by a manager?
Which virus can be eliminated from a colony by embryo rederivation?
Which statement accurately describes the immunosuppressive properties of NSAIDs compared with glucocorticoids?
An abnormal urinalysis may indicate disease of which organ of the body?
Which of the following statements applies to chronic immune complex diseases?
Which class of biosafety cabinets protects the user against direct contact with the contents of the cabinet?
What type of respirator is most typically used in animal facilities?
Which feature distinguishes gene-targeted mutation from pronuclear injection?
Which agency is associated with the Practitioner's Manual used for controlled substances?
How often do USDA APHIS personnel make unannounced inspections of a research facility?
Which category describes the policy that animals experiencing pain or distress and receiving relief are classified under?
What is a good way to ensure that weekend work assignments are covered and do not cause resentment among the staff?
Which of the following practices may potentially compromise security of an animal facility?
Which graft involves tissue transplanted between different species?
The antibody-mediated response is also called the ___________ response.
After thawing a set of frozen embryos for line recovery, what is the next action?
What is the best way to motivate someone working for you?
Prostaglandin is a hormone derived from what type of compound?
What condition is indicated by microfilaria found in fresh blood smears of a dog?
Which of the following is a common cause of a high red blood cell count?
The statement that bacteria contain nucleic acids while viruses do not is:
What is the most reliable indicator that a chimera can pass a targeted mutation through the germline?
Which statement about diethyl ether is accurate?
Which characteristics apply to synthetic corticosteroids?
Regularly scheduled testing for tuberculosis is necessary for all personnel who work with what species?
Sulfonamides are broad spectrum antibiotics.
A primary immunodeficiency disease is an acquired condition resulting from an infection or a side effect of a drug treatment.
Which outcome is directly associated with establishing personal goals?
What term refers to eliminating parasites by giving the animal an anthelmintic drug?
Which document serves as a guide for the care and use of laboratory animals?
Which of the following statements about unannounced inspections is true?
Which temperature activates the heat-sensitive tape used to monitor cage wash cycles?
Serum chemistry tests help the veterinarian determine which organ might be affected in a sick animal.
If the P value is set at 0.05, what is the confidence level?
Which term best describes the cells that present antigens to trigger a broader immune response?
Under the 1985 amendment, the manner of exercise for dogs must be determined by whom?
Rate setting for an institution is usually determined by which of the following?
Which is the most abundant immunoglobulin in mammalian serum?
In statistics, a normal distribution is also known by what other term?
What is the term for animals used in the health surveillance of rodent colonies?
When a Standard Operating Procedure has been revised, what should be done with the older copy?
Which component is not part of a DNA nucleotide?
Which standard reflects what USDA inspectors look for during an inspection?
All pinworm infections in rodents can be detected by the anal tape test.
What is true of the enteric coating that is used for some drugs?
The management function that involves creating a formal structure and defining roles is called:
A bacterium requiring normal atmospheric oxygen concentration to survive is called:
Which delivery method described uses a cotton ball on a cone covering the animal's snout?
What is the recommended order of steps in hiring staff?
If there is a deviation on a lab animal housing room checklist, the manager should do which of the following?
Which observation can be used to ensure the integrity of a particular strain of animal?
Amperage is the measure of:
When measuring antibody titers, a lower titer indicates less antibody is present. True or false?
What best defines an antibody titer?
What is the primary reason for establishing and maintaining a breeding colony in a research facility?
When a controlled substance is used, the inventory sheet should indicate the amount used and which animal received the drug.
What group of parasites is generally flat dorsoventrally, has suckers, and has larval forms that hatch in water?
PCR can detect pathogens in immunodeficient animals.
Which sign could suggest dermatophytosis?
True or False: Diarrhea treatment in nonhuman primates sometimes includes anticholinergic or antisecretory drugs.
What is an appropriate starting point for preparing a budget of expenses for the next fiscal year?
Ringworm is an example of which type of disease?
Ferrets are susceptible to which of the following diseases?
Which nucleotide is unique to RNA and not used in DNA?
Which route should be used to give barbiturate anesthetics to effect?
Fungal diseases cannot be diagnosed by culturing a sample because they don't grow in culture. True or false?
Naloxone is an opioid antagonist used to reverse opioid effects.
Which immunoglobulin class is most commonly associated with allergic reactions such as asthma?
For the repair and maintenance of facility equipment and premises, the manager needs to coordinate with which individuals?
Signs such as pruritus, hair loss, and skin lesions are usually indicative of an endoparasitic infestation.
Who should represent the animal facility on the institution's safety committee according to the described guidance?
Gloves made from which of the following materials would be best to use when handling nonhuman primates?
In employee occupational health training, which of the following is included?
In creating a transgenic line, what is the purpose of mating founders from pronuclear injection to wild-type?
Which stage of anesthesia should be attained before tracheal intubation?
What is the recommended approach when interpersonal conflicts occur?
Which of the following is a step involved in goal-setting?
The review of revenues and costs should be compared at least __ to identify any adjustments that need to be made for variances.
Dense areas of the body absorb the most X-rays. How do these areas typically appear on radiographs?
Genetic engineering advances have enabled which types of studies?
Serum is the liquid that remains after blood has been allowed to clot.
Which of the following is an example of what would be done in the preparedness step in disaster planning?
Which scenario applies to the production of chimeras?
Which cell type is commonly associated with the early, non-specific defense against pathogens?
Which statement about endotracheal intubation is true?
Which of the following is a defined index used to assess breeding performance?
Which virus is associated with ectromelia and a generalized body rash in mice that survive infection?
The main difference between bacteria and viruses is that bacteria contain nucleic acids and viruses do not.
The best time to monitor for microbial antibodies is when the animals are nursing.
Specific Pathogen Free (SPF) animals are defined as being free of which of the following?
An issue that must be considered in the development of a disaster plan includes which of the following?
Infectious agents, oncogenic viruses, and recombinant DNA are all considered ______________ hazards.
Kaopectate is used to treat which condition in laboratory animals?
Which parasites are mosquitoes capable of transmitting as vectors?
Which of the following parasites is a zoonotic agent?
Which areas should be assessed in the development of an occupational health program?
If the plasma appears cloudy in the hematocrit tube, it could be an indication of what condition?
Fusing a plasma cell with a tumor cell creates ______ that are used to produce__________.
Which of the following is used to measure the specific gravity of urine?
Which of the following would be considered a direct cost in animal facility budgeting?
Flatworms, roundworms, and thorny-headed worms all belong to which group of parasites?
Axemic animals have an intestinal wall that is _____________ than in animals with a normal microflora.
A Schedule I substance has _____ potential for addiction than a Schedule III substance.
A drug given intravenously reaches peak concentration in the bloodstream more rapidly than when given subcutaneously.
Where does replication take place?
In performance feedback, which area should be the primary focus to drive improvement?
Maintenance dose is best described as which of the following?
Pancuronium is classified as which drug type?
Which parasite has cats as the true definitive host in its life cycle?
Which statement about vaporizer use is true?
Which item is not explicitly listed as a factor to assess in the development of an occupational health program?
Which characteristic does NOT apply to diethyl ether?
For a drug with the same dose, which route generally has the slowest onset of action?
Which definition best describes a transgene?
Heat lamps are the best equipment for maintaining the animal's body temperature during long surgical procedures.
In the animal facility, who has the primary responsibility for the safe handling and disposal of hazardous waste?
Antibodies are a type of:
Which inhalant gas can be used in combination with isoflurane?
Which of the following types of animals are completely free of all detectable microorganisms?
Which measure is essential in establishing an effective facility security plan?
What is Saprolegnia?
Which statement would best describe the relationship between facilities housing the same species and disaster plan uniformity?
Which of the following drugs is a benzodiazepine tranquilizer?
The tidal volume for most laboratory animals is ____ ml/kg.
Which statement best describes the mirror principle?
Which drug is an alpha-2 adrenergic agonist?
Most regulated medical waste is generally regulated at the ______ level.
Which statement applies to mousepox?
Cestodes belong to which broad group of animals?
Where would you normally expect to find ectoparasites on a rabbit?
Which statement correctly describes intravenous administration relative to other routes for peak concentration?
The route of administration affects the time to onset of drug effect.
Bremsstrahlung is an X-ray produced when beta particles decelerate.
In the zebrafish experiment, which is the independent variable?
What best describes a peptide?
Which of the following is essential for isolator systems?
Which leukocyte has characteristic red granules in its cytoplasm when stained with Wright's stain?
Which radiographic technique can provide moving pictures?
Which animal species can be infected by LCMV according to the material?
The term axenic refers to animals that are
The bioavailability of a drug varies according to its route of administration.
What is the most common side effect of NSAIDs?
It is important to carefully follow the experimental design to avoid introducing unwanted ___________ that could affect the experimental results.
Subclinical diseases are typically diagnosed by which method?
Which of the following must be included in protocols for GLP studies?
Nitrous oxide can be used in combination with isoflurane.
To coordinate resources to achieve goals is the main purpose of organizing in facility management.
Are all documents stored in the facility inspectable by USDA APHIS inspectors?
Which unit is used to describe light intensity in this context?
In the process of creating transgenic animals, what technique often involves injecting DNA into the pronucleus of a fertilized egg?
Which statement best describes the relationship between genes and chromosomes?
A respirator must be maintained in accordance with which specifications?
Cats are the true definitive host for which parasite listed below?
Which of the following processes describes recovering a mouse line?
What is the standard fiscal budgetary period of time?
In a facility security incident, which group is identified as the first responders?
What is the cause of a low litter size in axenic gerbils?
LATGs can make a significant contribution to the development of the unit's goals because of their:
Dense areas of the body absorb the most X-rays.
The genetic make-up of an organism is called its __________.
At what stage of anesthesia are reflexes lost?
Which route is absorbed through mucosa of the gastrointestinal tract?
The AWA amendments of 1985 require that enrichment be provided to promote psychological well-being of which species?
Acetylpromazine is categorized as which type of drug?
In the sequence of steps in the acquired immune response, what step directly follows recognition?
Which security measure is described as a tool to monitor facility activity and deter unauthorized access?
Under the Hazard Communication Standard, which is required to help ensure chemical safety by listing all hazardous chemicals in the workplace?
Which characteristics promote good management of a facility's Standard Operating Procedures?
Animals that have a normal intestinal flora but are free of particular disease-causing organisms are called what?
Which of the following characteristics are true of fur mites?
Deworming is used to remove which stage of helminth parasites?
What is the most efficient way to manage your 'to do' list?
Which of the following types of research facilities are generally thought to be at the lowest risk of being targeted by animal rights activists?
Which of the following organisms would not cause enteritis in hamsters?
What agency has regulations that control the receipt, possession, use, transfer, and disposal of nuclear materials?
Which of the following is an example of a direct cost?
Who has the ultimate responsibility for ensuring that the facility has met training requirements?
Nude mice lack a thymus and so don't produce:
Chimera production typically involves introducing embryonic stem cells into which embryonic stage?
When planning a biomedical study, when are the design aspects typically finalized?
Work with moderate risk agents that are associated with human diseases of varying severity should be performed at what ABSL level?
Antidiarrheal drugs are used to treat the symptoms but not the cause of diarrhea.
Control of helminth infections typically includes which two components?
Superficial mycoses may be caused by which organism?
What is the meaning of the term 'confidence level' as used in biomedical research?
The same drug may have different effects when administered by different routes.
What virus may not be clinically apparent but may cause an increased death rate during anesthesia in rats?
What are bacteria that can grow in low oxygen environments called?
Dividing the workload based on what an average person can reasonably accomplish within regular working hours is a basic principle of:
Which of the following statements does NOT apply to annelid parasites?
What surface in a biosafety cabinet should be wiped with a decontaminating solution before and after each work session?
The foster mother used to raise axenic mice should have had her own litter no more than how many days before the donor's pups are put in her cage?
Which organization accredits research institutions that meet national laws and guidelines?
Which arm of the acquired immune system is primarily mediated by T lymphocytes?
Sensitization refers to what phenomenon in pharmacology?
Which method is commonly used to monitor for mouse hepatitis virus in a colony?
Which quick method is used to detect endoparasites but is not very accurate?
Which assay is most commonly used to detect exposure to viral pathogens in laboratory animals?
Canine distemper virus often causes fatal respiratory infections in dogs.
Which activity is generally done by the staff of the purchasing department?
If you observe unsatisfactory behavior in an employee, you should counsel the employee only after you have observed the behavior three times.
Which of the following statements is NOT true about mouse parvovirus?
Which pathogen presents a zoonotic risk?
What term describes an animal carrying a transgene on one chromosome but not on the homologous chromosome?
Which of the following statements does NOT describe characteristics of the acquired immune system?
Which two cell types fuse to form hybridomas?
When obtaining animals for research, the purchase order must include which of the following?
When is the best time to provide feedback about work performance?
In nonhuman primates, treatment for diarrhea often includes anticholinergic or antisecretory drugs.
What best defines 'randomization' in biomedical research?
Which route is used for barbiturate anesthetics to effect, according to the material?
Which statement best describes 'community right-to-know' regulations?
Employee occupational health training in the animal facility should include which of the following?
Isolators must always be operated with positive pressure with respect to the room.
Ketamine is commonly used in conjunction with which type of drug in large animals?
Which activity is used to allocate internal support costs to cost centers?
FOIA and E-FOIA make available which category of documents from research facilities?
What is the best route of injection for an irritating drug?
What publication is considered the standard by which all occupational health programs involving research animals are measured?
The most important role of the immune system is to keep foreign substances from entering the blood circulation.
When is the experimental design of a research protocol developed?
Genotype is the term used to describe an organism's genetic make-up.
The expenses associated with all the regulatory compliance efforts by an institution represent which type of cost?
What does the term prognosis mean?
Which of the components of the innate immune system coat the surface of invading organisms to facilitate their attack by macrophages?
The white blood cell differential determines the ratio of white to red blood cells.
In radiography, the more radiolucent the organ, the darker it will appear.
Lymphocytic choriomeningitis virus (LCMV) is a zoonotic organism which may infect mice and hamsters.
Which statement best describes the goal of a quality assurance program?
Which method is best for reducing physical space costs?
Which two diseases can be transferred from humans to nonhuman primates in an animal facility?
Which of the following signs are often observed along with diarrhea in nonhuman primates?
A trypanosome infection would most likely be found in which species?
In rooms using microisolation cages, sentinels are housed in cages that contain ______ from other cages in the room.
What route is the highest risk for introducing pathogens into an animal facility?
Which factor is a main consideration when determining the number of sentinel animals?
Which characteristic applies to Bacillus stearothermophilus?
In drug administration, what does the term vehicle mean?
Which statement about spores is correct?
Which organization has developed standards and guidelines to help prevent the transmission of zoonoses via the importation of animals?
Which of the following are small particles that move at high speed and are moderately penetrating of tissue?
Which statement best differentiates direct costs from indirect costs in a laboratory facility?
Which option would improve clarity and usefulness when writing Standard Operating Procedures?
Developing a reporting structure can be classified as what kind of activity?
PCR is commonly used for what purpose in genetic monitoring?
Bacterial gill disease in fish may be caused by which of the following?
Biochemical markers used to monitor genetic integrity include:
Which question is acceptable to ask in an interview?
The final decision about which drug used to treat a sick animal must be made by the veterinarian after consultation with which individual?
Acetylpromazine is best described as which type of drug?
Which cells are most directly responsible for producing antibodies after activation?
Which of the following is not a good suggestion for writing clear Standard Operating Procedures?
Who usually establishes most of the unit's goals?
In what year was the Animal Welfare Act amended to require dogs to be exercised in a manner determined by a veterinarian?
Which of the following is NOT a component of the innate immune system?
When an infectious disease spreads among a colony of rodents, what is often the most effective method to eradicate it?
Giardia spp. are ___________ that live in their host's gastrointestinal tract.
Which of the following is an example of a radioisotope?
Which statement about mouse hepatitis virus is true?
What publication gives detailed descriptions of the different biosafety levels that are used to describe work with infectious agents?
Which of the following steps should a lab animal facility manager take to ensure that the supplies and equipment purchased meet the needs of the facility?
What disposal method is most generally used for medical waste?
Mixing a drug into the animal's daily food ration ensures that all the medication is ingested.
What is the best way to determine if protozoan cysts are present in an animal?
Which statement describes the open drop system for inhalation anesthesia?
In the three-step goal-setting process, which is the second step?
Which best describes passive immunity?
Why is cyclosporin A often used in individuals who have received tissue transplants?
The laryngeal reflex is generally maintained during surgical anesthesia.
In goal-setting, which action is directly involved in determining resources needed?
Which description describes an animal that carries the transgene in only one copy of a chromosome pair (and lacks it on the homolog)?
Parasites are multicellular organisms that live in or on their hosts.
Which statement describes complementary base pairing in DNA?
What does ELISA stand for?
Which documents are available through FOIA and E-FOIA?
In N-95 respirators, what does the 'N' indicate?
Which statement should describe how animal purchase numbers are tracked relative to protocol approval?
Which statement describes progressive discipline in the workplace?
Which document should be the basis for semiannual IACUC inspections?
Levels of light photo intensity above 75 foot-candles can cause which type of injury in albino animals?
Promotion primarily satisfies which category in Maslow's hierarchy?
What best describes a polyvalent vaccine?
During transgenic mouse creation, which developmental stage is typically used for DNA injection to create the transgene?
Personnel should be encouraged to report the presence of anyone who is in the animal facility and who does not seem familiar with its layout.
Which description best describes category C animals?
In transgenic mouse work, what generation immediately follows the founder?
Which agency/requirement is associated with ensuring that institutions describe the essential components of their animal use and care program?
Propofol can be given as a continuous intravenous infusion.
The fact that about 80% of mouse genes have a corresponding gene in the human genome suggests what about mammalian genomes?
A low platelet count may indicate a tendency to develop what condition?
What is an advantage of NSAIDs over glucocorticoids?
Which statement best describes fungal reproduction?
What is another term used for the blood test called hematocrit?
Steroids are what type of compound?
Serology primarily examines the presence of what in serum?
An institution's disaster plan should include ways to deal with which of the following situations?
What does the generation called F2 represent among transgenic mice?
Which of these animals should be fasted overnight if it is to be intubated?
The ability to clearly relate the facility's goals to the staff is an example of:
Otitis externa in dogs is always due to bacterial infection.
What is another term for infectious tracheobronchitis in dogs?
Who establishes the expiration date of a drug product?
Liquid nitrogen should always be stored in a sealed leak-proof container.
What is the first priority to consider in the event of a disaster?
When wild type females are bred to hemizygous males, what percentage of the offspring can be expected to have the transgene?
What term describes infestation by mites?
Which of the following is an example of a revenue-producing cost?
Endotracheal intubation is required for inhalation anesthesia.
In transgenic research, what is the main advantage of uniform phenotypes among animals?
What is the minimum age for sentinel animals?
What is the advantage of using decentralized lab animal facilities?
Which statement best describes a potential impact of vermin on facility operations?
Enrofloxacin belongs to what group of antibacterial drugs?
For working with volatile agents, which equipment is best?
Feline lower urinary tract disease occurs more frequently in which type of animal?
Which characteristic best describes a coccoid bacterium?
Which item is commonly included under the Medical Waste Tracking Act as medical waste?
Which anesthetic drug is often found in euthanasia preparations?
What does the acronym MFI stand for?
The beginning of modern gnotobiotic research dates back to the 1950s when _________ became available.
In statistical analysis, what is the term used to describe how spread out the individual measurements are from one another?
Patches of differently colored fur in chimeras prove germline transmission of the targeted mutation.
What are direct costs?
Which statement about antibodies is correct?
A pre-anesthetic treatment may be used to:
For producing gene-targeted animals, the dosage and timing of the hormone injections to produce superovulation must take into consideration which of the following factors?
Ketamine is categorized as which type of agent?
Which statement describes the purpose of enteric coating?
Under FDA GLP, which area is not typically required to have a standard operating procedure?
Which term describes a drug interaction where one drug increases the effect of another?
Which of the following activities must be done regularly in order to maintain the water quality in automatic watering systems?
Which pairing correctly matches skill type with the described example?
Which are the recommended types of feedback for employee performance evaluations?
In pharmacology, a structure-activity relationship refers to the process associated with which of the following?
Which health condition in rabbits presents with anorexia, no feces, and a palpable abdominal mass?
Autoimmune disease is characterized by the immune system reacting against which of the following?
Statistics show that about ____ % of the people who work with laboratory animals develop allergic symptoms.
Which of the following is an example of histopathology?
Which graft type uses tissue transplanted from the same individual?
A urine sample with high specific gravity indicates what about the urine?
Which suggestion would be most effective for ensuring staff compliance with the security plan?
Which measure would be most effective at reducing personnel costs?
Antibiotics are used to combat what type of infections?
The ________ provides the body with its first line of defense against foreign substances.
What is a "necropsy"?
What daily practice supports consistent task completion in a lab animal facility?
Which feedback statement best focuses on the action rather than the person?
Rotating weekend assignments among staff helps ensure fairness.
What is the mean of a group of measurements?
Pyrethrins are what type of substance?
How can you make sure that an employee understands your explanation of completing a task?
Per diem increases are problematic because they are often paid from fixed grants based on previous rates.
What is a major problem that a new supervisor often faces when organizing workload?
Regularly backing up important computer files would be considered what type of disaster-related activity?
In management, which term best describes the ongoing activity of checking progress and performance over time?
In an experiment, which term best describes the variable measured to observe effects?
What is the mean of a group of measurements?
In rebreathing machines, the size of the rebreathing bag should be determined by which factor?
If a manager wants to reduce turnover by increasing scheduling flexibility, which practice should be adopted?
USDA APHIS inspectors have the authority to:
Which device is used to measure blood pressure in small animals?
Which of the following does a pulse oximeter NOT measure?
Which method is the preferred method of eliminating mouse parvovirus from a colony?
Which statement best describes a typical secondary (anamnestic) immune response?
Rectal prolapse in mice is most commonly associated with infection by which genus?
Noise and vibrations in an animal facility commonly cause what changes in rodents?
Food remains in the intestinal tract longer in axenic animals than in normal animals.
Which of the following publications provides additional clarifications and guidance in support of the Animal Welfare Act?
What method may be used to determine histocompatibility and immune response when evaluating transgenic mouse strains?
Which is an example of good feedback?
Which species is known to suffer from scurvy due to a vitamin C deficiency?
Which action best aligns with limiting facility access to IACUC-approved individuals?
Which characteristic is true of all bacteria?
All animals must be evacuated in the event of any disaster.
Gastric trichobezoars in rabbits present with which clinical sign?
Which of the following statements about vaccination against the rabies virus is true?
Polyclonal antibodies are defined as groups of antibodies that bind to which site on an antigen?
A rapid onset of anesthesia is achieved by using an inhalant anesthetic with low solubility.
What is a common method used to detect exposure to viral pathogens?
To increase confidence level, you should lower the P value threshold.
Which goal best describes the use of transgenic models in biomedical research?
All facilities housing the same type of animals and engaged in similar types of research should have the same disaster plans.
Which component is a noncellular part of the innate immune system?
The humoral immune response is primarily associated with antibodies circulating in body fluids.
Which statement correctly describes hematocrit and packed cell volume?
Which species is explicitly noted as being susceptible to infection with human influenza virus?
Which institutional office generally has the responsibility for monitoring the handling of radioactive materials in the laboratory?
Which Maslow level is most closely associated with benefits like retirement plans?
If the white area of the NFPA diamond affixed to a container has a "W" on it, what should you be careful about when working with that substance?
What does an ultrasonic Doppler flow detector measure?
Which term describes the complete genetic content of an organism?
Which of the following drugs is an opioid?
Flea larvae are an intermediate host for which of the following?
Repairing the facility after a disaster would be considered what type of disaster-related activity?
What is a key feature of effective SOP management?
Haploid cells are primarily found in the gonads.
Dipylidium caninum is a tapeworm; what is the general class to which it belongs?
Which of the following is true about antibiotics?
Where would you expect to find Dirofilaria immitis during the necropsy of a dog?
The presence of lipids in plasma causing a hazy appearance in hematocrit tubes is called:
Which of the following is a cause of otitis externa in dogs?
In rodent facilities, what action is often necessary to stop an outbreak when infection is widespread?
Controlled substances are classified by federal regulations into how many schedules?
Iron, sodium, and potassium are examples of what type of elements?
The ability to maintain a good rapport with upper management and outside agencies represents which type of skill?
How often should a research facility using regulated species update their USDA registration?
Vitamins partner with which of the following to help maintain normal cell functions?
Which of the following is a good people management practice?
Cell-mediated immune response is triggered by which kind of cells?
In the radiology lab, what resource provides guidance on the settings for radiographing an animal?
Monitoring during axenic derivation includes checking for the absence of which organism to prevent transplacental transmission?
What is the main goal of maintaining sentinels in animal rooms?
Which action best supports a sense of belonging and social connection among employees?
Which of the following statements correctly describe the PHS assurance?
Which phrase best describes the term 'antigen'?
As a supervisor, which of the following would be expected as part of your job duties?
In the area of occupational health and safety, what does the acronym LAA stand for?
Depressed levels of neutrophils usually indicate what disease or condition?
Which carbohydrate among the listed is a monosaccharide?
Dose rates are generally expressed as:
In disaster planning, which action demonstrates preparedness for a power outage?
During USDA inspections, facilities must demonstrate compliance with provisions of which federal regulations?
Which statement accurately reflects feline lower urinary tract disease risk factors?
Miconazole is what type of drug?
A common practice is to limit facility access only to those individuals who are listed on IACUC approved protocols.
What requirement was added in the 1985 Amendment to the Animal Welfare Act regarding dogs?
What best describes a transgenic animal?
Mouse hepatitis virus and minute virus of mice are never subclinical.
The study of fungi is called?
Ivermectin use requires caution in which group of dogs?
For small scale accidents in the facility, in what order should the following three steps be taken?
Penicillin is the best antibiotic to treat mice, rats, hamsters, and guinea pigs.
What term is used to describe cells that present antigens to other immune cells?
Which methods are used to detect pinworm infection?
Good Laboratory Practices regulations apply to non-clinical studies.
Which statement is not an acceptable way to give feedback about handling cages?
Albon® and Tribrissen® are examples of which kind of antibiotics?
Which testing method is commonly used to assess exposure to viral pathogens in laboratory animals?
Prions are infectious agents consisting only of what type of biomolecule?
According to the Good Laboratory Practice regulations, the Quality Assurance unit shall:
Which organization is also known for setting international animal health standards to prevent disease transmission via animal importation?
What is the primary purpose of 'community right-to-know' regulations in this context?
Pinworm eggs are usually destroyed by heat or dessication.
What is the scolex in a tapeworm?
In phenylketonuria, which of the following substances is in higher than normal concentration in the blood and tissues?
Which observation is a valid indicator of strain identity including genetic status?
Which statements about fleas, lice, and mite-related conditions are true?
Which practice would NOT help prevent disease spread in a laboratory animal colony?
Which of the following statements is true of the innate immune system?
What are the two characteristics of medical waste that are used to determine if the waste material is considered infectious?
Which laboratory rodent is particularly prone to epileptic seizures?
Which is the best description of schedule II drugs?
The use of ivermectin should be avoided or carefully controlled in which group of animals?
Which term describes the rate at which a drug is absorbed from the site of administration?
Capillary refill time is best described as which of the following?
What kind of cells is used to produce transgenic mice by gene-targeted mutations?
Which metric unit equals one millionth of a meter?
Which blot technique is used to detect proteins?
Which organism would not cause enteritis in hamsters? (Alternate phrasing)
Environmental monitoring systems should be in place to continuously monitor which of the listed items?
A generalized body rash and ectromelia are often present in animals that survive infection from which virus?
Schaedler cocktails, or altered Schaedler cocktails, are defined as
Identical twins have the same set of MHC proteins.
Ribosomes take part in which cellular activity?
By which method are most endoparasites detected?
If a transgene is integrated in one of the chromosomes of a pair, the animal is said to be:
If an animal's blood oxygen level is normal, what color are its mucous membranes?
True or False: A candidate who meets the minimum requirements for the job is a better choice than an overqualified candidate.
What are the basic components of proteins?
Which statement is true of a subclinical disease?
Which term describes the set of proteins expressed by the genome at a given time?
What best describes recombinant DNA?
Which statement best describes plasma relative to clotting in blood samples?
What is another term for reverse tolerance to a drug?
Which characteristic is NOT used to classify microorganisms?
Recertification at specific intervals is required for which equipment?
To preserve tissues for further examination, what is the usual ratio of tissue to fixative used, by weight?
All areas around the animal facility building should be kept dark except around the entrances.
Which base pair is found in DNA?
What is the most effective strategy for ensuring that daily lab animal care tasks are completed?
To obtain axenic pups, the hysterectomy on the donor female is best done how many hours prior to natural parturition?
Which statement best describes the role of the QA unit under GLP?
If a researcher plans to reuse an animal for multiple major surgeries, what documentation must accompany the plan?
In an X-ray machine, what is the voltage related to?
A compound that may be toxic to the kidneys may be generated when the anesthetic gas __ passes through a soda lime canister.
What does a p-value of 0.05 imply about the significance of results according to the material?
You are trying to determine the effect of raising water temperature from 25.5°C to 27°C on the survival rate of zebrafish in a tank that contained 1000 fish. Water temperature is kept constant at 27°C for a period of 4 weeks. What is the independent variable?
Valence determines which property of an atom?
Axenic animals have lower requirements for which nutrient?
Which disease may cause anesthetic complications in pigs?
Which statement best describes the role of a hypothesis in research?
Which of the following carbohydrates is a monosaccharide?
What is the minimum time period that all USDA reports and records must be kept after completion of the study?
What cellular organelle is the site of protein synthesis?
The purchase order for obtaining animals must include which element to ensure compliance?
A transplant from a pig to a human is an example of what type of graft?
What is the role of cytokines?
Exposure to acoustic levels above what decibel level can have harmful effects?
What are "CFUs?"
What best describes genetic drift?
Which of the following is a correct precaution for personnel handling hazardous waste?
Which unit is commonly used to report RBC counts?
The concentration of which of the following is usually expressed as grams per deciliter (g/dL)?
Where would you find haploid cells?
Which statement about lice eggs is true?
“PDR” is the acronym for which of the following?
What are two alternative methods used to reduce or eliminate the noise typically used in traditional fire alarms?
In ferrets, insulinomas develop in which organ?
What did the 1989 amendments require for the care of non-human primates?
Mange in dogs is caused by which type of parasite?
B Cells and Plasma Cells are part of the __________-Mediated Immune Response.
In animal facilities, which arachnid parasite is most commonly encountered?
Giving an employee a promotion would satisfy which Maslow need?
What measurement is obtained in an anesthetized dog, when you apply finger pressure on the gums for one second and then release this pressure?
Which description is NOT true for antibodies?
Cyclosporin A is used in transplant patients mainly because it does what?
The best approach to an inspection is to provide only the information and records requested by the inspectors.
Which method is not primarily used to detect endoparasites?
Semiannual inspections conducted by the IACUC should:
Which test would be most informative for evaluating the shape and size of red blood cells?
What is the goal of a quality assurance program?
Which disaster-related activity is focused on reducing the severity of a potential incident before it occurs?
Do research requirements affect staff scheduling and workloads?
Which acronym corresponds to a multiplex assay using fluorescent labels?
Which statement defines the 3-step process of goal setting?
Molds generally grow more slowly than bacteria.
What is a good reference for those responsible for managing controlled substances?
Too few cages available on Monday morning is an example of which type of constraint?
When a radiograph is taken, X-rays penetrate the body.
What type of bonds connect complementary bases across the two DNA strands?
Which observation would indicate a dam is providing good maternal care to her pups?
Which item is NOT part of the Hazard Communication Standard guidelines and requirements?
Which approach most effectively introduces a new task to staff?
Altered Schaedler cocktails are described as
The athymic mouse's immunodeficiency can be classified as what type of disease?
The purpose of periodically comparing revenues and costs in a cost analysis is to identify:
What does CBC stand for?
Heating devices used to maintain the body temperature of anesthetized animals should be ____°F higher than normal?
Which practice should be in place to ensure proper handling of animal shipments on delivery?
Axenic animals have lower requirements for Vitamin A; which statement reflects this?
Rectal prolapse in mice is commonly caused by which common bacterium?
Which term is synonymous with the inhalation of medications?
Leukocytes generally make up 6-8% of the total blood volume.
Providing each staff member with specific training regarding Good Laboratory Practices is the responsibility of the institution's:
Which statement best describes diploid cells?
Which measure is used to assess peripheral perfusion by pressing on the gums?
Which route is associated with rapid systemic distribution for an irritating drug?
Viruses are visible under a light microscope.
Which practice leads to fewer employees leaving incomplete projects at the end of the day?
Which statement about fungi is true?
What is the best way to make sure that employees understand how to perform a new task?
USDA inspection reports are available to the public through the Freedom of Information Act (FOIA).
What is a hypothesis?
Old World primates are highly susceptible to which zoonotic disease?
The most effective method for eliminating mouse hepatitis virus is cesarean or embryo transfer rederivation.
High concentrations of neutrophils or heterophils are usually indicative of what disease or condition?
Which statement about self-nonself distinction is true according to the described role of MHC proteins?
Steroids are categorized as which type of biomolecule?
What are the three steps involved in an acquired immunity response to a foreign substance?
Which of these characteristics is NOT used to classify microorganisms?
All the cells of a chimera are derived from the mutant ES cells which were injected into the blastocyst.
Under the Animal Welfare Act, which agency conducts annual inspections of animal facilities?
What is the general shape of antibodies?
X-rays are made up of what types of waves?
An imbalance in the different types of lipoproteins (HDL versus LDL) is a major contributing factor in which of the following diseases?
Germline transmission is demonstrated when the mutation is observed in offspring.
Which statement best describes the general microbial status of axenic animals?
Which anatomical feature is enlarged in axenic animals?
Detergents and disinfectants are not considered hazardous chemicals.
Which document is described as providing essential clarifications in support of the Animal Welfare Act?
Which component of the innate immune system is known for coating pathogens to promote phagocytosis by macrophages?
Which phase describes the period in a primary response when antibody levels first become measurable?
Which of the following diseases is zoonotic?
All USDA inspection reports are available to anyone who requests them.
Which of the following are internal support costs?
Assigning all lab animal facility budgetary items to specific categories is valuable because it allows for which event?
Which biomolecule is analyzed to determine if a transgene is present in an animal's cells?
A transplant from one inbred mouse to another mouse of the same strain is an example of what type of graft?
Suspensions are liquids in which the drug is dissolved.
Which of the following is a type of electromagnetic radiation that is generated nonradioactively?
What is a practical sign that SOPs are being actively maintained in a facility?
Which statement best applies to Good Laboratory Practices regulations?
Which of the following is a good security measure for staff?
The pressure gauge on an oxygen tank accurately reflects the amount of gas remaining.
If a mouse no longer looks pregnant and no pups are visible, the technologist can examine the mouse's ______ for evidence of birthing.
To be compliant with OLAW, what document should be the basis of the IACUC review of the institution's program for the use and care of animals?
What is the primary benefit of limiting access by non-staff visitors in animal colonies?
To draw blood for a test that uses plasma, you should make sure the syringe contains an anticoagulant.
Which zoonotic viral disease often remains asymptomatic in infected macaques and can be fatal in humans?
Which organization accredits research institutions that meet national laws and guidelines?
Which agency conducts inspections to ensure compliance with the Animal Welfare Act in laboratory settings?
What does a pulse oximeter measure?
Coprophagy in rabbits must be taken into consideration in which circumstance?
Which route among the following best bypasses the gastrointestinal tract?
Which statement best describes the primary benefit of cryopreservation for mouse strains?
Organizing an employee athletic program helps meet which Maslow need?
Which of the following is true of antibodies?

AALAS Laboratory Animal Technologist (LATG) Practice Test

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